Model fitting to cell cycle marker dynamics obtained from MCF-10A cells processed data.

<p>Four cell cycles of experimental data obtained from processed data of untreated MCF-10A cells is shown in blue dots (moving median) with their respective median absolute deviations for each marker; (A) cyclin-dependent kinase inhibitor, ; (B) cyclin D, ; (C) E2F active, ; (D) cyclin E, ; (E...

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Bibliographic Details
Main Author:	Javiera Cortés-Ríos (9997940) (author)
Other Authors:	Maria Rodriguez-Fernandez (140484) (author), Peter Karl Sorger (22386471) (author), Fabian Fröhlich (848026) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Cell Biology Physiology Biotechnology Immunology Developmental Biology Cancer Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Information Systems not elsewhere classified rendering larger bodies different initial conditions devise training strategies model training approaches propose data processing condition immunofluorescence data cells exhibit oscillatory cell cycle arrest cell cycle model cell cycle data accessible cell types unsynchronized cells time techniques technical challenges static snapshots predictive power phosphorylation markers multiple protein mathematical modelling integrating multiplexed integrated single hitherto made dynamic trajectories dynamic processes dynamic modelling development trajectories arrested dynamics
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Model fitting to cell cycle marker dynamics obtained from MCF-10A cells processed data.

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