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<div><p>Cytochrome P450 enzymes (P450s), particularly those of microbial origin, are highly versatile biocatalysts capable of catalyzing a broad range of regio- and stere-oselective reactions. P450s derived from extremophiles are of particular interest due to their potential tolerance to...

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Detalles Bibliográficos
Autor principal:	Hande Mumcu (22208676) (author)
Otros Autores:	Julian Zaugg (4867477) (author), Irem Keles (22208679) (author), Aycan Kayrav (22208682) (author), Nurgul Balci (6186566) (author), David R. Nelson (43435) (author), Philip Hugenholtz (13833) (author), Elizabeth M. J. Gillam (14002745) (author), Nevin Gul Karaguler (22208685) (author)
Publicado:	2025
Materias:	Biochemistry Microbiology Genetics Biotechnology Evolutionary Biology Ecology Inorganic Chemistry Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified responsive metabolic pathways particular interest due mine drainage site including hydrothermal springs harsh environmental conditions functional gene annotation 138 metagenomic bins microbial community compositions extreme environments across exploring extreme environments enabling microbial adaptation shotgun metagenomic analysis including 45 high 49 new subfamilies p450s ), particularly rkiye &# 8217 microbial origin extreme habitats phylogenetic analysis high temperature 158 subfamilies &# 252 p450s derived novel p450s work provides untapped potential sequence diversity quality metagenome potential tolerance p450 enzymes oselective reactions novel biocatalysts industrial relevance hypersaline lakes future studies findings highlight broad range biotechnological applications assembled genomes 87 families
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