TEM quantifications.

<div><p>The spore-forming intestinal pathogen <i>Clostridioides difficile</i> causes multidrug resistant infection with a high rate of recurrence after treatment. Piscidins 1 (p1) and 3 (p3), cationic host defense peptides with micromolar cytotoxicity against <i>C</i...

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Bibliographic Details
Main Author:	Adenrele Oludiran (17827388) (author)
Other Authors:	Areej Malik (17827391) (author), Andriana C. Zourou (17827394) (author), Yonghan Wu (17827397) (author), Steven P. Gross (17827400) (author), Albert Siryapon (17827403) (author), Asia Poudel (17827406) (author), Kwincy Alleyne (17827409) (author), Savion Adams (17827412) (author), David S. Courson (17827415) (author), Myriam L. Cotten (1310271) (author), Erin B. Purcell (2277322) (author)
Published:	2024
Subjects:	Biophysics Biochemistry Microbiology Cell Biology Pharmacology Biotechnology Immunology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified nickel binding motif forming intestinal pathogen div >< p amino terminal copper bacterial cell walls piscidins generally sensitize defense piscidin peptides 2 +</ sup clostridioides difficile </ difficile </ piscidins 1 >, sensitize c </ vesicle mimics two peptides targets dna sublethal concentrations study highlights peptides reveal peptides leads microscopy monitoring micromolar cytotoxicity lower doses holo states high rate epidemic strain effects obtained different forms condense dna cell membrane antimicrobial peptides antibiotic adjuvants adjuvant effect
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TEM quantifications.

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