The 44 MT variants selected by Vijay.

The 44 MT variants selected by Vijay.

<div><p>Mitochondrial (MT) mutations serve as natural genetic markers for inferring clonal relationships using single cell sequencing data. However, the fundamental challenge of MT mutation-based lineage tracing is automated identification of informative MT mutations. Here, we introduced...

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Bibliographic Details
Main Author: Xuexin Yu (733842) (author)
Other Authors: Jing Hu (41899) (author), Yuhao Tan (15227659) (author), Mingyao Pan (21587178) (author), Hongyi Zhang (431841) (author), Bo Li (112195) (author)
Published: 2025
Subjects:
Genetics
Molecular Biology
Evolutionary Biology
Cancer
Infectious Diseases
Plant Biology
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
xlink "> mitochondrial
natural genetic markers
mutated cancer cells
inferred evolutionary lineage
existing methods measured
informative mitochondrial mutations
benchmarked mitotracer using
based lineage tracing
informative mt mutations
mutations serve
work provided
valuable tool
superior performance
mt mutation
mitotracer facilitates
inhibitor resistance
high sensitivity
genes related
fundamental challenge
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