ATGL-1 levels increase and lipid droplets decrease in response to <i>N. parisii</i> infection.

ATGL-1 levels increase and lipid droplets decrease in response to <i>N. parisii</i> infection.

<p>(A-B) <i>atgl-1::gfp</i> L1 stage <i>C. elegans</i> were cultured for a total of 72 hours and were either left uninfected or infected for 24, 48, or 72 hours. (A) Representative fluorescence images of live adult <i>atg-1::gfp</i> worms. White lines indica...

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Bibliographic Details
Main Author: Hala Tamim El Jarkass (16625309) (author)
Other Authors: JiHae Jeon (21637626) (author), Nicholas O. Burton (21637629) (author), Aaron W. Reinke (840430) (author)
Published: 2025
Subjects:
Biochemistry
Microbiology
Genetics
Immunology
Cancer
Infectious Diseases
Computational Biology
Biological Sciences not elsewhere classified
natural microsporidian pathogen
limited metabolic capabilities
infect many types
div >< p
host genes involved
nematocida parisii </
caenorhabditis elegans </
host fat levels
microsporidia infection alters
parisii </
elegans </
host metabolism
using lipidomics
triglyceride levels
significantly change
microsporidia infection
lipid metabolism
lipid levels
lipid enzymes
infection levels
infection decreases
infection causes
increased ceramides
ceramide synthesis
cause changes
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