Volcano plot with the –log10 transformed unadjusted p-values versus the log fold change from the differential abundance analysis on the different taxonomic levels found in vaginal samples of healthy breeding bitches analyzed by Next Generation Sequencing.

Volcano plot with the –log10 transformed unadjusted p-values versus the log fold change from the differential abundance analysis on the different taxonomic levels found in vaginal samples of healthy breeding bitches analyzed by Next Generation Sequencing.

<p>The horizontal line marks the significance level, i.e., –log10(0.05). While a few features are significant according to the raw <i>P</i>-value, significance is lost after <i>P</i>-value adjustment.</p>

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Bibliographic Details
Main Author:	Anna Sophia Leps (21192402) (author)
Other Authors:	Eva-Maria Packeiser (8575059) (author), Christina Schwens (21192405) (author), Benjamin Stoelcker (21192408) (author), Semir Doric (21192411) (author), Martina Wirkner (21192414) (author), Beate Walter (21192417) (author), Axel Wehrend (8638347) (author), Viktoria Kichmann (21192420) (author), Klaus Jung (65489) (author), Sandra Goericke-Pesch (4812366) (author)
Published:	2025
Subjects:	Microbiology Genetics Evolutionary Biology Ecology Developmental Biology Science Policy Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified previous studies investigating made notable advances canine vaginal bacteria fertility mostly relied canine vaginal microbiome balanced vaginal microbiome correlate ngs data healthy breeding bitches vaginal sample fertility data successful breeding breeding examination ngs revealed ngs analysis ngs ), diverse microbiome xlink "> statistical analysis routine pre recent years provide evidence often thought litter size larger differences independent methods important prerequisite healthy litters generation sequencing first study blood sample become popular became pregnant aerobic culturing
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