Composition of intestinal microbial communities in the large intestine of rats before and after <i>T. gondii</i> infection.

Composition of intestinal microbial communities in the large intestine of rats before and after <i>T. gondii</i> infection.

<p><b>(A–B)</b> Bar plots illustrating taxonomic composition at the phylum and species levels across different groups before and after infection. <b>(C)</b> Box plots depicting the relative abundance of major bacterial phyla, including <i>Verrucomicrobiota</i&g...

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Главный автор: Ji-Xin Zhao (22056386) (author)
Другие авторы: Wen-Bin Zheng (3328680) (author), Shi-Chen Xie (10678094) (author), He Ma (583317) (author), Xiao-Tong Chen (4217488) (author), Ying-Qian Gao (22683622) (author), Lu-Yao Tang (22683625) (author), Meng-Ting Yang (10714266) (author), Fu-Long Nan (22056395) (author), Jing Jiang (130103) (author), Hany M. Elsheikha (6910232) (author), Xiao-Xuan Zhang (610969) (author)
Опубликовано: 2025
Предметы:
Biochemistry
Microbiology
Cell Biology
Genetics
Physiology
Ecology
Immunology
Computational Biology
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
showed negative associations
quality reads produced
oxidative stress response
conducted metagenomic sequencing
compositional changes coincided
bile acid transformation
aromatic compound processing
7 million genes
rothia nasimurium </
lactobacillus intestinalis </
de novo </
untargeted serum metabolomics
specific metabolic disruptions
amino acid metabolism
toxoplasma gondii </
limosilactobacillus reuteri </
lactobacillus johnsonii </
akkermansia muciniphila </
host systemic metabolism
disrupts intestinal microbiota
reuteri </
muciniphila </
johnsonii </
gondii </
host metabolism
untargeted lc
metabolic targets
energy metabolism
infection disrupts
significant shifts
reduced abundance
rat model
positively correlated
pathways related
novel microbial
microbial diversity
metabolites implicated
marked reduction
marked depletion
key role
immune modulation
gut microbiota
findings demonstrate
enhanced glycan
disease mechanisms
comprehensive non
community structure
chronic stages
active enzymes
18 sprague
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