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<div><p>Duchenne muscular dystrophy (DMD) is a X-linked neuromuscular disorder arising from mutations in the dystrophin gene, leading to a progressive muscle wasting and disability. Currently there is no universal therapy, and there is thus a strong interest in preclinical studies for fi...

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Bibliographic Details
Main Author:	Brigida Boccanegra (11104155) (author)
Other Authors:	Roberta Lenti (20189569) (author), Paola Mantuano (9975816) (author), Elena Conte (169190) (author), Lisamaura Tulimiero (15210073) (author), Richard J. Piercy (9415958) (author), Ornella Cappellari (3172365) (author), John C. W. Hildyard (4637164) (author), Annamaria De Luca (9975831) (author)
Published:	2024
Subjects:	Biochemistry Medicine Cell Biology Genetics Molecular Biology Developmental Biology Marine Biology Cancer Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified replicate key features quantitative pcr analysis multiple possible scenarios evaluate therapeutic efficacy duchenne muscular dystrophy div >< p ></ sup >< >< sup >< identify stable references candidate references (< specific comparative scenarios progressive muscle wasting finding novel treatments monitor disease progression analyzed using genorm normalizing gene expression examined gene expression gc ), diaphragm characterized mouse model novel model gene expression poor references specific changes muscle type dystrophin gene recent model wt ), widely used validated empirically universal therapy universal panels type controls strong interest sdha </ rpl13a </ results illustrate preclinical studies pak1ip1 </ normfinder algorithms measurements must mdx </ md </ matched wild large panel important tool human disease htatsf1 </ hprt1 </ hmbs </ gapdh </ csnk2a2 </ conversely revealed better mimics b10 -< ap3d1 </ actb </ >) mouse 52 weeks 10scsn -<
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