a) Score distribution for hexapeptides present in Amyloid Atlas. The distribution shape resembles that of all hexapeptides, with similar means. Black line represents the probability density function for the Amyloid Atlas dataset.

<p>The dataset mean is -21.23 ± 4.13 REU. b) zif comparison of the solved core vs full-length proteoform sequences for 9 notable amyloids. The cores, on average, have higher zif scores than their full length sequences but not statistically significant (p = 0.586).</p> <p>(TIF)</...

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主要作者:	Samantha Zink (22120627) (author)
其他作者:	Songrong Qu (22120630) (author), Thomas Holton (491084) (author), Eesha Shankar (22120633) (author), Paulina Stanley (22120636) (author), David S. Eisenberg (1325538) (author), Michael R. Sawaya (217747) (author), Jose A. Rodriguez (1982692) (author)
出版:	2025
主題:	Biophysics Biochemistry Molecular Biology Pharmacology Developmental Biology Plant Biology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Chemical Sciences not elsewhere classified Information Systems not elsewhere classified xlink "> predicting predictive model allows predictions show enrichment like structures remain cell wall reorganization amyloid formation across zipper forming segments steric zipper propensity informed machine learning machine learning zipper profiles peptide segments amyloid fold adopt amyloid ten years recent progress rapid proteome proteome level proteins involved potential category new approach facilitated structure experimental characterization designed sequences based prediction
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a) Score distribution for hexapeptides present in Amyloid Atlas. The distribution shape resembles that of all hexapeptides, with similar means. Black line represents the probability density function for the Amyloid Atlas dataset.

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