Quantitative analysis of ABC transporters transcripts.

Quantitative analysis of ABC transporters transcripts.

<p><b>(A)</b> Distribution of <i>Aae</i>ABCA2, <i>Aae</i>ABCB1, <i>Aae</i>ABCC2 and their paralogous genes in the <i>A. aegypti</i> chromosomes. <b>(B)</b> The expression level of paralogous genes of <i>Aae</i>...

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Autor principal:	Sabino Pacheco (372889) (author)
Altres autors:	Marcos Chiñas (11635765) (author), Juan Ulises Gómez (21656025) (author), Ángel Enrique Peláez-Aguilar (21656028) (author), Nathaly Alexandre do Nascimento (21656031) (author), Pablo Emiliano Cantón (8262417) (author), Jorge Sánchez (2204284) (author), Samira López-Molina (10005222) (author), Isabel Gómez (833406) (author), Mario Soberón (322907) (author), Alejandra Bravo (322909) (author)
Publicat:	2025
Matèries:	Biochemistry Microbiology Cell Biology Genetics Molecular Biology Physiology Pharmacology Evolutionary Biology Ecology Cancer Inorganic Chemistry Infectious Diseases Chemical Sciences not elsewhere classified wild type strains redundant receptor function findings provide evidence div >< p avoiding resistance development similar larvicidal activity bacillus thuringiensis </ apical microvilli membrane aedes aegypti </ histopathological analysis showed abc transporters knockout abc transporter orthologs insecticidal cry toxins cry toxins binding abc ko mutation cry toxins insecticidal activity abc transporters abc </ vivo </ transporter genes membrane proteins binding assays abc ko cry receptors using crispr transcriptomic regulation significant reduction potentially contribute paralogous genes insect larvae induces upregulation gut tissue gut epithelium genome corresponding fitness cost cry11ba ). could mitigate compensatory mechanism coleopteran species
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