Ultra-Photostable Fluorescent Boron-Bridged Near-Infrared Probes to Reveal New Mode of Lipid Droplet-Mitochondria Interaction at STED Super-Resolution

Ultra-Photostable Fluorescent Boron-Bridged Near-Infrared Probes to Reveal New Mode of Lipid Droplet-Mitochondria Interaction at STED Super-Resolution

Interactions between lipid droplets (LDs) and mitochondria are vital for maintaining the cellular metabolism and energy homeostasis. However, visualizing these interaction dynamics at a high resolution in live cells is still very challenging. Here, a boron-bridged near-infrared probe (<b>QI-BF...

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Bibliographic Details
Main Author: Mingyue Cao (4221919) (author)
Other Authors: Xiaoming Zhu (710820) (author), Yunting Liu (4503139) (author), Yangang Su (385425) (author), Xinru Hu (11535205) (author), Zhiqiang Liu (182265) (author), Xiaoqiang Yu (128293) (author)
Published: 2025
Subjects:
Biophysics
Biochemistry
Medicine
Cell Biology
Biotechnology
Plant Biology
Virology
Computational Biology
Chemical Sciences not elsewhere classified
study sheds light
reveal new mode
mitochondrial wrapping around
exhibited excellent photostability
enabled continuous scanning
commercial mitochondrial dyes
96 mw cm
power sted nanoscopy
photostable fluorescent boron
mediated mitochondria tubulation
bf </ b
color sted super
sted super
sted laser
successfully captured
resolution visualization
resolution interactions
resolution imaging
morphological interactions
mitochondria interaction
live cells
lipid droplets
lipid droplet
interaction dynamics
infrared probes
high resolution
frames using
first time
energy homeostasis
dynamic process
dynamic dual
developed specifically
cellular metabolism
bridged near
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