Data Sheet 14_Enterohemorrhagic Escherichia coli O157 outer membrane vesicles administered by oral gavage cause renal tubular injury and acute kidney failure in mice.pdf

Data Sheet 14_Enterohemorrhagic Escherichia coli O157 outer membrane vesicles administered by oral gavage cause renal tubular injury and acute kidney failure in mice.pdf

Background<p>Outer membrane vesicles (OMVs) secreted by enterohemorrhagic Escherichia coli (EHEC) O157 contain Shiga toxin 2 (Stx2), the major virulence factor involved in the pathogenesis of EHEC-associated hemolytic uremic syndrome (EHEC-HUS). However, it remains unclear whether EHEC OMVs pr...

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Detalhes bibliográficos
Autor principal: Jaromír Háček (22671836) (author)
Outros Autores: Alena Vlková (22671839) (author), Daniel Krsek (11595178) (author), Lukáš Kolařík (22671842) (author), Alžběta Spálenková (22671845) (author), Tomáš Sychra (22671848) (author), Tereza Tesařová (22671851) (author), Emin Gayibov (22671854) (author), Radka Václavíková (606637) (author), Jakub Zieg (11416838) (author), Martina Bielaszewska (79970) (author)
Publicado em: 2025
Assuntos:
Clinical Microbiology
enterohemorrhagic Escherichia coli (EHEC)
Shiga toxin
outer membrane vesicles
mouse model
oral gavage
hemolytic uremic syndrome
renal tubular damage
acute kidney failure
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