Image5_Activating STAT3 mutations in CD8+ T-cells correlate to serological positivity in rheumatoid arthritis.jpeg

Image5_Activating STAT3 mutations in CD8+ T-cells correlate to serological positivity in rheumatoid arthritis.jpeg

Objectives<p>Large granular lymphocyte (LGL) leukemia is a rare hematologic malignancy characterized by clonal expansion of cytotoxic T-cells frequent somatic activating STAT3 mutations. Based on the disease overlap between LGL leukemia rheumatoid arthritis (RA)a putative role for CD8+ T-cells...

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Main Author: Katharine B. Moosic (19920009) (author)
Other Authors: Thomas L. Olson (19920012) (author), Mark Freijat (19920015) (author), Samara Khalique (19920018) (author), Cait E. Hamele (4885351) (author), Bryna Shemo (19920021) (author), Jesse Boodoo (19920024) (author), William Baker (3285705) (author), Gitanjali Khurana (19920027) (author), Matthew Schmachtenberg (19920030) (author), Tristin Duffy (19920033) (author), Aakrosh Ratan (279792) (author), Erika Darrah (573352) (author), Felipe Andrade (227564) (author), Marieke Jones (13228897) (author), Kristine C. Olson (392022) (author), David J. Feith (8654346) (author), Donald L. Kimpel (19920036) (author), Thomas P. Loughran (8654349) (author)
Published: 2024
Subjects:
Immunology
Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies)
Autoimmunity
Cellular Immunology
Humoural Immunology and Immunochemistry
Immunogenetics (incl. Genetic Immunology)
Innate Immunity
Transplantation Immunology
Tumour Immunology
Immunology not elsewhere classified
Genetic Immunology
Animal Immunology
Veterinary Immunology
rheumatoid arthritis
large granular lymphocytic leukemia
anti-citrullinated protein antibodies
CD8-positive T-lymphocytes
rheumatoid factor
stat3
JAK/STAT
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