Establishment of a senescence-related graft survival prognostic model.

Establishment of a senescence-related graft survival prognostic model.

<p><b>A.</b> Univariable Cox regression analysis screening prognostic SRGs. <b>B.</b> Ten-fold cross-validation selecting λ in LASSO model. <b>C.</b> LASSO coefficient profiles of 12 pSRGs. The optimal λ = 4 was selected. <b>D.</b> Coefficients o...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Xihao Shen (20347942) (author)
مؤلفون آخرون: Jiyue Wu (3814717) (author), Feilong Zhang (420300) (author), Qing Bi (3864823) (author), Zejia Sun (10031646) (author), Wei Wang (17594) (author)
منشور في: 2024
الموضوعات:
Cell Biology
Genetics
Molecular Biology
Neuroscience
Biotechnology
Developmental Biology
Marine Biology
Cancer
Virology
Computational Biology
weighted gene co
two clusters underscored
multiple established databases
machine learning algorithms
integrative machine learning
gene expression omnibus
demographic shift towards
consensus clustering algorithm
b >(</ b
aged donor kidneys
term graft outcomes
expression network analysis
differential expression analysis
comprehensive analysis underscores
worse graft survival
reduced graft survival
predicting graft survival
two rejection clusters
rejection remains elusive
optimal acute rejection
delayed graft function
ktx rejection poses
ktx rejection occurrence
identify predictive srgs
invasive diagnostic model
kidney transplant rejection
graft survival
ktx rejection
kidney graft
diagnostic model
kidney rejection
gsva analysis
cluster analysis
allograft function
rejection samples
diagnosing rejection
prognostic model
kidney transplantation
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wgcna ),
significant threat
related genes
provided microarray
positive correlation
level landscape
ischemic damage
detailed cellular
conducted using
conclusions drawn
cluster c1
c2 ).
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