Module 1 (M1), the primary mechanism (PM), and Module 2 (M2), the secondary mechanism (SM) under normal (NC) and stressful (SC) conditions along with the phosphorylation and dephosphorylation reactions (PdP).

<p>A: Primary mechanism of translation initiation under normal and stressful conditions. This network captures all the interactions involving e5 and e2B with e2 and the phosphorylation and dephosphorylation reactions. B: Bifurcation diagram of e2pGDP with total kinase (kin<sub>T</sub&...

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Bibliographic Details
Main Author:	Guturu L. Harika (20917923) (author)
Other Authors:	Krishnamachari Sriram (11665756) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Cell Biology Genetics Molecular Biology Marine Biology Infectious Diseases Computational Biology Biological Sciences not elsewhere classified robust ternary complex many signaling proteins make quick decisions integrated stress response apply bifurcation theory kinetic modelling reveals initiation stage based primary reaction mechanism primary mechanism involves model exhibits ultrasensitivity active dimer eif2 translation initiation process secondary mechanisms involved initiation process initiation mechanism translation initiation safe mechanism mathematical model kinetic parameters dimer binds two mechanisms switching mechanisms safe mechanisms elementary mechanisms ribosome recycling invoked instantaneously high fidelity experimental observations controlled intricately compactly categorized
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Module 1 (M1), the primary mechanism (PM), and Module 2 (M2), the secondary mechanism (SM) under normal (NC) and stressful (SC) conditions along with the phosphorylation and dephosphorylation reactions (PdP).

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