The results of mitochondrial dysfunction related proteins with potential therapeutic drug molecular docking.

The results of mitochondrial dysfunction related proteins with potential therapeutic drug molecular docking.

<p><b>(A)</b> DLAT docking results with NADH, Radicicol, and Dihydrolipoic Acid. <b>(B)</b> DLD docking results with NADH, Flavin adenine dinucleotide, and Glycine. <b>(C)</b> FDX1 docking results with Mitotane. <b>(D)</b> PDHA1 docking results w...

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Bibliographic Details
Main Author: Tingting Liu (267387) (author)
Other Authors: Jingwen Li (314020) (author), Junshi Zhang (9404552) (author), Jianshe Wei (18435783) (author)
Published: 2025
Subjects:
Biochemistry
Cell Biology
Genetics
Molecular Biology
Biological Sciences not elsewhere classified
various analytical methods
transmission electron microscopy
process potentially leading
potential therapeutic drugs
parkinson &# 8217
neurodegenerative condition characterized
modulating copper metabolism
mirna network highlighted
induced mouse model
31 distinct modules
expression network analysis
differential expression analysis
potential hub genes
identify module genes
uncovered mitochondrial alterations
potential pd treatments
differentially expressed cuproptosis
differential gene expression
early pd diagnosis
disease </ p
related genes associated
related genes
protein analysis
analysis led
related pathways
mitochondrial function
mitochondrial dysfunction
pd prevention
pd ),
thereby enhancing
sy5y cells
study concluded
remaining five
motor deficits
kyoto encyclopedia
intersecting degs
internal training
including nadh
geo database
gene ontology
external validation
enrichment analyses
dopamine neurons
designating one
degs ).
additional scrutiny
9 ),
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