Imatinib treatment increases cytokine production in BMDMs.

Imatinib treatment increases cytokine production in BMDMs.

<p><b>A-F.</b> BMDMs derived from C57BL/6J mice infected with Mm at an MOI of 10 for 8, 24 or 44 hrs at 37°C. RNA was isolated from the cells and qPCR was used to measure mRNA levels of <i>tnf</i> <b>(A),</b> <i>il12b</i> <b>(D),</b>...

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Bibliographic Details
Main Author:	Tesia L. Cleverley (15628353) (author)
Other Authors:	Siri Peddineni (15628356) (author), Jeannette Guarner (10332569) (author), Francesca Cingolani (12174410) (author), Pamela K. Garcia (6392888) (author), Heather Koehler (15628359) (author), Edward S. Mocarski (8628189) (author), Daniel Kalman (42478) (author)
Published:	2023
Subjects:	Medicine Microbiology Ecology Immunology Cancer Infectious Diseases tail lesions indicates substantially alter anti related tyrosine kinases mycobacterium tuberculosis complex may mitigate post may facilitate development limiting pathology associated div >< p data provide evidence cancer drug used regulating immune responses delayed immune response new therapeutic approaches limits pathology associated contain bacterial spread mycobacterial immune responses mycobacterium marinum </ mycobacterial infections cause induce widespread morbidity culture following infection mycobacterial infections immune activation limits rate directed therapeutic bacterial clearance vivo </ vitro </ infections caused transcriptomic analysis targets abl surrounding tissue promotes survival promote survival nontuberculous mycobacteria lung damage lesion size later ones key regulator infection model histological measurements derived macrophages cell survival causing tb bone marrow also contribute
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