Recombinant mapping narrows region of interest to identify a loss-of-function allele of <i>mttp.</i>

Recombinant mapping narrows region of interest to identify a loss-of-function allele of <i>mttp.</i>

<p>A) markers A<sub>a</sub> and B<sub>a</sub> were outputted by WheresWalker and used to genotype <i>arches</i> mutants in order to identify recombinants. M and F denote male and female parents, respectively. PCR product sizes for wild-type and mutant (highl...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: McKenna Feltes (11242085) (author)
مؤلفون آخرون: Aleksey V. Zimin (8363328) (author), Sofia Angel (21714119) (author), Nainika Pansari (21714122) (author), Monica R. Hensley (3133671) (author), Jennifer L. Anderson (15991713) (author), Meng-Chieh Shen (4608190) (author), Mackenzie Klemek (21714125) (author), Yi Shen (152956) (author), Vighnesh S. Ginde (21714128) (author), Hannah Kozan (21714131) (author), Nhan V. Le (21714134) (author), Vivian P. Truong (21714137) (author), Meredith H. Wilson (6816489) (author), Steven L. Salzberg (8363331) (author), Steven A. Farber (9217109) (author)
منشور في: 2025
الموضوعات:
Medicine
Microbiology
Genetics
Neuroscience
Evolutionary Biology
Infectious Diseases
Virology
Environmental Sciences not elsewhere classified
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
supports positional cloning
method using mutants
forward genetic screening
allelic frequency calculations
whereswalker correctly mapped
sequencing approach based
previously unappreciated apob
previously published mutation
div >< p
sequencing algorithm
powerful approach
describe whereswalker
slc3a2a </
potential candidates
mttp </
modifying locus
mia2 </
lipoprotein metabolism
key step
gene causing
drastically reduces
assign functions
1 </
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة