Subset pedigrees of the SNP genotyped cases, their close relatives and initial homozygosity mapping.

<p>(<b>A</b>) Red filled symbol are dogs clinically affected. Males are indicated with squares; females are indicated with circles; half-filled symbols are putative heterozygotes. Family history indicated that the parents and siblings were unaffected suggesting recessive inheritanc...

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Bibliographic Details
Main Author:	Leonardo Murgiano (492751) (author)
Other Authors:	Jessica K. Niggel (22756468) (author), Kei Takahashi (57099) (author), Valérie L. Dufour (22756471) (author), Catharina R. Grubaugh (22756474) (author), Raghavi Sudharsan (693733) (author), Jennifer C. Kwok (16830567) (author), Doreen Becker (247005) (author), Esha Banerjee (14561037) (author), Wen-Mei Yu (583065) (author), Tosso Leeb (81674) (author), Cheng-Kui Qu (25237) (author), William A. Beltran (11828609) (author), Gustavo D. Aguirre (11828606) (author)
Published:	2025
Subjects:	Medicine Genetics Neuroscience Developmental Biology Biological Sciences not elsewhere classified unclear even though ultrastructure expansion microscopy genetically engineered mice div >< p asp361glufster2 ), reducing actual causative gene >-/- knockout mice 3 ’- end functional candidate validation retinal rna analysis inherited retinal diseases specific opsins detected rod abnormalities suggesting contributory role towards >- related form 954 – 60 two different genes gene large deletion early onset blindness two genes large deletion functional refinement day blindness retinal phenotype retinal degeneration onset day retinal disease work shows vision loss truncated transcripts transition zone still present standard poodle splicing suggests spata7 deficiency spata7 </ segregated perfectly rod dystrophy ptpn21 loss ptpn21 </ progressive later primary cilium predicted protein phenotype within onset disease one culprit ocular phenotype mutant allele main cause human patients
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Subset pedigrees of the SNP genotyped cases, their close relatives and initial homozygosity mapping.

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