Enhancements to SarcGraph’s z-disc segmentation pipeline.

<p>(A) Starting from a raw cell image with all detected contours shown in blue, each contour is processed individually to crop a pixel region centered on it (current processing contour highlighted in yellow). This region serves as the image representation of the processing contour and is trans...

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Bibliographic Details
Main Author:	Saeed Mohammadzadeh (13492285) (author)
Other Authors:	Emma Lejeune (11530267) (author)
Published:	2025
Subjects:	Biochemistry Biotechnology Cancer Space Science Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified Information Systems not elsewhere classified two key enhancements novel ensemble graph modified sarcgraph algorithm minimally invasive manner individually detected sarcomere data using information predict expert scores cells often exhibit cm structural integrity source dataset published mature cardiomyocytes exhibit highly organized structure cms &# 8212 cm structural organization structural organization quantify structure organized sarcomeres mature samples expert scoring derived cardiomyocytes cardiac cells structural features xlink "> valuable model scoring approach results demonstrate longer myofibrils important indicator immature cells identify bias functional behavior first time explainable clustering enhanced framework disease models disc classifier designed specifically densely packed deeper understanding deep learning computational tools cell science cell maturity better accommodate based z allen institute
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Enhancements to SarcGraph’s z-disc segmentation pipeline.

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