Data Sheet 1_GM-CSF and IL-21-armed oncolytic vaccinia virus significantly enhances anti-tumor activity and synergizes with anti-PD1 immunotherapy in pancreatic cancer.docx

Data Sheet 1_GM-CSF and IL-21-armed oncolytic vaccinia virus significantly enhances anti-tumor activity and synergizes with anti-PD1 immunotherapy in pancreatic cancer.docx

<p>Pancreatic cancer is one of the most aggressive cancers and poses significant challenges to current therapies because of its complex immunosuppressive tumor microenvironment (TME). Oncolytic viruses armed with immunoregulatory molecules are promising strategies to overcome limited efficacy...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Yujing Xuan (8062175) (author)
مؤلفون آخرون: Wenyi Yan (9504903) (author), Ruimin Wang (317092) (author), Xibin Wang (3135924) (author), Yu Guo (102701) (author), Huilin Dun (20498258) (author), Ziyan Huan (20498261) (author), Lihua Xu (534555) (author), Ruxia Han (11053320) (author), Xianlei Sun (1697218) (author), Lingling Si (12704724) (author), Nicholas R. Lemoine (9125847) (author), Yaohe Wang (85674) (author), Pengju Wang (5019086) (author)
منشور في: 2025
الموضوعات:
Genetic Immunology
oncolytic vaccinia virus
GM-CSF
IL-21
pancreatic cancer
anti-PD1
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