A Simulation Study of the Role of Mechanical Stretch in Arrhythmogenesis during Cardiac Alternans

The deformation of the heart tissue due to the contraction can modulate the excitation, a phenomenon referred to as mechanoelectrical feedback (MEF), via stretch-activated channels. The effects of MEF on the electrophysiology at high pacing rates are shown to be proarrhythmic in general. However, mo...

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Bibliographic Details
Main Author: Hazim, Azzam (author)
Other Authors: Belhamadia, Youssef (author), Dubljevic, Stevan (author)
Format: article
Published: 2021
Online Access:http://hdl.handle.net/11073/25363
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