Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery

Ultrasound (US) increases efficacy of drugs delivered from micelles, but the pharmacokinetics have not been studied previously. In this study, US was used to deliver doxorubicin (Dox) sequestered in micelles in an in vivo rat model with bilateral leg tumors. One of two frequencies with identical mec...

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Bibliographic Details
Main Author: Staples, Bryant J. (author)
Other Authors: Pitt, William G. (author), Roeder, Beverly L. (author), Husseini, Ghaleb (author), Rajeev, Deepthi (author), Schaalje, G. Bruce (author)
Format: article
Published: 2010
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Online Access:http://hdl.handle.net/11073/21284
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