DNA damage induced by micellar-delivered doxorubicin and ultrasound: comet assay study
To minimize adverse side effects of chemotherapy, we have developed a micellar drug carrier that retains hydrophobic drugs, and then releases the drug by ultrasonic stimulation. This study investigated the DNA damage induced by doxorubicin (DOX) delivered to human leukemia (HL-60) cells from pluroni...
Saved in:
| Main Author: | Husseini, Ghaleb (author) |
|---|---|
| Other Authors: | El-Fayoumi, Refaat I. (author), O'Neill, Kim L. (author), Rapoport, Natalya Y. (author), Pitt, William G. (author) |
| Format: | article |
| Published: |
2000
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/11073/19827 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Comet Assay to Determine the Mode of Cell Death for the Ultrasonic Delivery of Doxorubicin to Human Leukemia (HL-60 Cells) from Pluronic P105 Micelles
by: Husseini, Ghaleb
Published: (2005) -
Kinetics of ultrasonic release of doxorubicin from pluronic P105 micelles
by: Husseini, Ghaleb
Published: (2001) -
Release of Doxorubicin from Unstabilized and Stabilized Micelles Under the Action of Ultrasound
by: Husseini, Ghaleb
Published: (2007) -
Investigating the mechanism of acoustically activated uptake of drugs from Pluronic micelles
by: Husseini, Ghaleb
Published: (2002) -
Optimizing the use of ultrasound to deliver chemotherapeutic agents to cancer cells from polymeric micelles
by: Husseini, Ghaleb
Published: (2011)