Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways

HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. It is characterized by aggressive behavior and treatment resistance. On the other hand, poly (amidoamine) (PAMAM) dendrimers are widely used in drug delivery systems and gene transfection a...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Hadeel, Kheraldine (author)
مؤلفون آخرون:	Gupta, Ishita (author), Alhussain, Hashim (author), Jabeen, Aayesha (author), Cyprian, Farhan S. (author), Akhtar, Saghir (author), Al Moustafa, Ala-Eddin (author), Rachid, Ousama (author)
التنسيق:	article
منشور في:	2021
الموضوعات:	PAMAMs HER2-positive Breast cancer Chemoprevention Apoptosis
الوصول للمادة أونلاين:	http://dx.doi.org/10.1016/j.csbj.2021.05.011 https://www.sciencedirect.com/science/article/pii/S2001037021001926 http://hdl.handle.net/10576/18454
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Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways

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