Neuronal BST2: A Pruritic Mediator alongside Protease-Activated Receptor 2 in the IL-27–Driven Itch Pathway

Neuronal BST2: A Pruritic Mediator alongside Protease-Activated Receptor 2 in the IL-27–Driven Itch Pathway

Chronic itch is a common and complex symptom often associated with skin diseases such as atopic dermatitis (AD). Although IL-27 is linked to AD, its role and clinical significance in itch remain undefined. We sought to investigate IL-27 function in itch using tissue-specific transgenic mice, various...

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Bibliographic Details
Main Author: Yanqing, Li (author)
Other Authors: Chen, Weiwei (author), Zhu, Xingyun (author), Mei, Huiyuan (author), Steinhoff, Martin (author), Buddenkotte, Joerg (author), Wang, Jinhai (author), Zhang, Wenhao (author), Li, Zhenghui (author), Dai, Xiaolong (author), Shan, Chunxu (author), Wang, Jiafu (author), Meng, Jianghui (author)
Format: article
Published: 2024
Subjects:
Atopic dermatitis
BST2
IL-27
itch
PAR2
Online Access:http://dx.doi.org/10.1016/j.jid.2024.01.025
https://www.sciencedirect.com/science/article/pii/S0022202X24001088
http://hdl.handle.net/10576/61709
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http://dx.doi.org/10.1016/j.jid.2024.01.025
https://www.sciencedirect.com/science/article/pii/S0022202X24001088
http://hdl.handle.net/10576/61709

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