Exploring global natural product databases for NLRP3 inhibition: Unveiling novel combinatorial therapeutic strategy for hidradenitis suppurativa

Exploring global natural product databases for NLRP3 inhibition: Unveiling novel combinatorial therapeutic strategy for hidradenitis suppurativa

BackgroundHidradenitis suppurativa (HS) is a chronic inflammatory skin condition of the terminal hair follicle, which can present in sporadic, familial, or syndromic forms. The exact pathogenesis of HS remains elusive, posing a challenge for the development of effective treatments. Among the various...

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Bibliographic Details
Main Author: Muhammad, Suleman (author)
Other Authors: Murshed, Abduh (author), Sayaf, Abrar Mohammad (author), Khan, Abbas (author), Khan, Salman Ali (author), Tricarico, Paola Maura (author), Moltrasio, Chiara (author), Agouni, Abdelali (author), Yeoh, Kar Kheng (author), Marzano, Angelo Valerio (author), Crovella, Sergio (author)
Format: article
Published: 2025
Subjects:
Hidradenitis suppurativa
NLRP3
Drug screening
Molecular dynamics simulation
Online Access:http://dx.doi.org/10.1016/j.jiph.2025.102697
https://www.sciencedirect.com/science/article/pii/S1876034125000462
http://hdl.handle.net/10576/64069
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http://dx.doi.org/10.1016/j.jiph.2025.102697
https://www.sciencedirect.com/science/article/pii/S1876034125000462
http://hdl.handle.net/10576/64069

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