Effects of internal carotid administration of MPTP on rat brain and blood-brain barrier
Unlike primates, rats are resistant to systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity, but direct infusion of MPTP into rat substantia nigra causes specific destruction of dopaminergic neurons. We now demonstrate that rats are resistant to MPTP neurotoxicity even when MPT...
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| Main Author: | Riachi, Naji J. (author) |
|---|---|
| Other Authors: | Dietrich, W. Dalton (author), Harik, Sami I. (author) |
| Format: | article |
| Published: |
1990
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| Online Access: | http://hdl.handle.net/10725/10436 https://doi.org/10.1016/0006-8993(90)91788-I http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.sciencedirect.com/science/article/pii/000689939091788I |
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