mTORC1 loss impairs epidermal adhesion via TGF-b/Rho kinase activation
Despite its central position in oncogenic intracellular signaling networks, the role of mTORC1 in epithelial development has not been studied extensively in vivo. Here, we have used the epidermis as a model system to elucidate the cellular effects and signaling feedback sequelae of mTORC1 loss of fu...
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| Main Author: | Georgess, Dan (author) |
|---|---|
| Other Authors: | Asrani, Kaushal (author), Sood, Akshay (author), Torres, Alba (author), Phatak, Pornima (author), Kaur, Harmisar (author) |
| Format: | article |
| Published: |
2017
|
| Online Access: | http://hdl.handle.net/10725/10343 https://doi.org/10.1172/JCI92893 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.jci.org/articles/view/92893 |
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