Spatiotemporal Dynamics of β-Adrenergic cAMP Signals and L-Type Ca2+ Channel Regulation in Adult Rat Ventricular Myocytes
Steady-state activation of cardiac β-adrenergic receptors leads to an intracellular compartmentation of cAMP resulting from localized cyclic nucleotide phosphodiesterase (PDE) activity. To evaluate the time course of the cAMP changes in the different compartments, brief (15 seconds) pulses of isopre...
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| Other Authors: | , , , , , , , |
| Format: | article |
| Published: |
2008
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| Online Access: | http://hdl.handle.net/10725/6356 https://doi.org/10.1161/CIRCRESAHA.107.167817 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.107.167817 |
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