Role of PDE3 and PDE4 for β-adrenergic control of cAMP and ICa,L in adult rat ventricular myocytes
β-Adrenergic stimulation increases cAMP in cardiac cells to induce PKA-mediated phosphorylation of various proteins regulating heart function, such as the L-type Ca 2+ channels which carry I Ca,L and trigger cardiac contraction. Phosphodiesterases (PDEs) 3 and 4 are the main cAMP degrading enzymes i...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | , , , , , , , |
| Format: | article |
| Published: |
2007
|
| Online Access: | http://hdl.handle.net/10725/6362 http://dx.doi.org/10.1117/j.yjmcc.2007.03.139 http://libraries.lau.edu.lb/research/laur/terms-of-use/articles.php https://www.jmmc-online.com/article/S0022-2828(07)00195-2/abstract#articleInformation |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|