Stimulating PV cells at nonsilencing levels during entire stimulus presentation or late phase V1 activity impairs discrimination performance, whereas stimulating during early phase V1 activity improves performance.
<p><b>A)</b> Example of grating stimuli separated by 90° for easy task (top), schematic of optogenetic manipulations activating only PV cells expressing ChR2 (middle), optogenetic stimulation timings for all four conditions aligned to stimulus onset (STIM ON) or offset (STIM OFF) (...
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2025
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