STAB1 or STAB2 expression increases THP-1 phagocytotic uptake of HLA-E coated beads (A) THP-1 dCas9 cells were transduced with a control guide or a guide targeting either LILRB1, STAB1 or STAB2 stained with HLA tetramers and analysed by flow cytometry.
<p>(B) THP-1 cells were incubated with HLA-E (VLA) coated microbeads at either 37°C or 4°C and analysed by flow cytometry. (C) THP-1 cells were incubated with fluorescent microbeads coated with peptide-loaded HLA molecules for either 1h or 24h and analysed using flow cytometry. The percentage...
محفوظ في:
| المؤلف الرئيسي: | Tom A. W. Schoufour (22421454) (author) |
|---|---|
| مؤلفون آخرون: | Linda Voogd (20466968) (author), Kees L.M.C. Franken (14983373) (author), Tom H.M. Ottenhoff (11686365) (author), Ruud H.M. Wijdeven (22421457) (author), Simone A. Joosten (11074623) (author) |
| منشور في: |
2025
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| الموضوعات: | |
| الوسوم: |
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مواد مشابهة
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CRISPR activation screen identifies STAB1 and STAB2 as novel interactors for HLA-E.
حسب: Tom A. W. Schoufour (22421454)
منشور في: (2025) -
STAB1 or STAB2 overexpressing cells interact with HLA-E presenting low affinity Mtb peptides, but not high-affinity HLA-I leader-sequence derived peptides (A) K562 dCas9 cells transduced with either a control guide or a guide targeting STAB1 or STAB2 were stained with HLA-E*01:03 tetramers used in the screen and analysed by flow cytometry.
حسب: Tom A. W. Schoufour (22421454)
منشور في: (2025) -
Conformation of the HLA-E/peptide complex is likely involved in the interaction with STAB1 or STAB2 (A) HLA-E monomers in complex with indicated peptides were exposed to increasing temperatures to measure their stability.
حسب: Tom A. W. Schoufour (22421454)
منشور في: (2025) -
Names, sequences and origin of peptides loaded in HLA-E in this study.
حسب: Tom A. W. Schoufour (22421454)
منشور في: (2025) -
<b>Proteogenomic discovery of novel open reading frames with HLA immune presentation on human beta cells</b>
حسب: Kathryn Walters (21988843)
منشور في: (2025)