The novel thioredoxin reductase inhibitor butaselen suppresses lung cancer by inducing oxidative stress

The novel thioredoxin reductase inhibitor butaselen suppresses lung cancer by inducing oxidative stress

<p>Lung cancer is one of the leading causes of cancer-related deaths worldwide with limited treatment options available. The anti-tumor effects of the TrxR inhibitor Butaselen (BS/BS1801) on lung cancer and its underlying mechanisms remain unknown.</p> <p>This study utilized lung c...

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Dettagli Bibliografici
Autore principale:	Yifan Chen (446592) (author)
Altri autori:	Guangliang Qiang (296666) (author), Liang Jin (316008) (author), Yan Sun (22436) (author), Guozhou Zhang (22688355) (author), Fengling Hu (3595472) (author), Jinhui Feng (269301) (author), Feng Wei (426184) (author), Shengxin Zeng (22688358) (author), Lixiang Xue (23235) (author), Huihui Zeng (6700337) (author), Shaohua Ma (8746758) (author)
Pubblicazione:	2025
Soggetti:	Biochemistry Medicine Microbiology Cell Biology Molecular Biology Pharmacology Developmental Biology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified Lung cancer oxidative stress thioredoxin reductase butaselen apoptosis high-mobility group box-containing protein 1 (HBP1) ubiquitination DNA methylation
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