The role of genetic and epigenetic GNAS alterations in the development of early-onset obesity
BackgroundGNAS (guanine nucleotide-binding protein, alpha stimulating) is an imprinted gene that encodes Gsα, the α subunit of the heterotrimeric stimulatory G protein. This subunit mediates the signalling of a diverse array of G protein-coupled receptors (GPCRs), including the melanocortin 4 recept...
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| Format: | article |
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2023
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| Online Access: | http://dx.doi.org/10.1016/j.mrrev.2023.108487 https://www.sciencedirect.com/science/article/pii/S1383574223000352 http://hdl.handle.net/10576/53084 |
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